Heart Failure with Normal Ejection Fraction: Understanding the Silent Threat
Heart failure with a normal ejection fraction (HFpEF) can seem confusing because it defies the usual expectations of heart failure. In most heart failure cases, the heart’s ability to pump blood (ejection fraction) is reduced. With HFpEF, your heart’s ejection fraction remains normal, but you still experience symptoms of heart failure. This condition, also known as diastolic heart failure, happens when the heart’s ventricles can’t properly relax and fill with blood.

You might feel shortness of breath, fatigue, and swelling in your legs, even though your heart’s pumping action appears normal. Diagnosing HFpEF requires not just observing symptoms but also looking closely at the heart’s function and structure. Luckily, understanding this condition better can lead to more effective management and treatments, helping you maintain a good quality of life.
By keeping the ejection fraction normal, HFpEF poses unique challenges and requires a different approach compared to other types of heart failure. Living with HFpEF means staying informed, having regular check-ups, and sticking to a treatment plan that works best for you and your lifestyle.
Key Takeaways
- HFpEF occurs when heart symptoms are present, but ejection fraction is normal.
- Diagnosis includes checking symptoms and heart function.
- Managing HFpEF involves regular monitoring and tailored treatments.
Understanding Heart Failure with Normal Ejection Fraction

Heart failure with normal ejection fraction, also known as diastolic heart failure, occurs when the heart is unable to fill properly, despite the ejection fraction being normal. This condition is especially common in older adults and people with certain health problems.
Defining Normal Ejection Fraction
The ejection fraction measures how much blood the left ventricle pumps out with each contraction. A normal ejection fraction ranges between 55% and 70%, implying that this amount of blood leaves the heart each time it beats. This number is important because it assesses how well your heart is functioning. Even if your ejection fraction is normal, you can still have heart failure, known as heart failure with preserved ejection fraction (HFpEF).
Epidemiology and Prevalence
Heart failure affects millions of people worldwide. In populations, heart failure with normal ejection fraction accounts for about 50% of all heart failure cases. Research like the Framingham Heart Study shows that HFpEF is especially prevalent among older adults, affecting more women than men. Diastolic heart failure is becoming more common due to the ageing population and the rise in health issues like diabetes and high blood pressure.
Causes and Risk Factors
Various conditions can lead to heart failure with normal ejection fraction. High blood pressure (hypertension) and diabetes are significant causes because they strain the heart over time. Other risk factors include obesity, coronary artery disease, and ageing. Hypertrophic cardiomyopathy and amyloidosis can also contribute to the condition. In some cases, congenital heart disease and LV hypertrophy (left ventricular hypertrophy) play a role. Recognising and managing these risk factors is crucial to reducing the chance of diastolic heart failure.
Diagnosis, Treatment, and Management

Diagnosing heart failure with normal ejection fraction (HFpEF) involves recognising specific symptoms and using various diagnostic tests. Treatment includes medications, lifestyle changes, and in some cases, advanced therapies. Long-term management focuses on maintaining heart health and preventing worsening symptoms.
Clinical Features and Symptoms
Heart failure with normal ejection fraction often presents with breathlessness, fatigue, and swelling in the legs and feet due to water retention. You might experience chest pain, wheezing, and even coughing. Other signs include weakness and sometimes nausea. It’s common for symptoms to worsen during physical activity or when lying down, which can severely impact daily life.
Diagnostic Tests
An echocardiogram is crucial for diagnosing HFpEF, as it measures the heart’s ejection fraction and assesses diastolic dysfunction. You may also need a cardiac catheterisation to check for heart blockages. MRI and CT scans provide detailed images of the heart’s structure. Chest X-rays can reveal fluid in the lungs, while a nuclear stress test evaluates blood flow during physical activity. These tests help pinpoint the exact cause of symptoms and guide treatment.
Effective Treatments
Medications are often the first line of treatment. Diuretics help reduce fluid buildup, easing swelling and breathlessness. ACE inhibitors, beta-blockers, and calcium channel blockers can improve heart function and control blood pressure. In cases of arrhythmias like atrial fibrillation, taking drugs such as digoxin may be necessary. Sometimes, devices like an implantable cardioverter defibrillator (ICD) can be used to manage severe symptoms and prevent dangerous heart rhythms.
Long-term Management
Managing HFpEF over the long term includes several lifestyle changes. Regular exercise and physical activity are essential but should be done under medical supervision, often through a cardiac rehabilitation programme. Maintaining a healthy weight and dietary adjustments to lower sodium intake can help control blood pressure. It’s also crucial to monitor fluid intake to prevent water retention. Consistent follow-ups with your healthcare provider ensure that any changes in symptoms are quickly addressed.
Frequently Asked Questions

Heart failure with normal ejection fraction is a condition where the heart pumps normally but cannot fill properly. Understanding the symptoms, treatment options, and distinctions in this condition is important.
What are the common symptoms associated with heart failure when ejection fraction remains normal?
Common symptoms include fatigue, shortness of breath, and swelling in the legs, ankles, or feet. You might also experience difficulty exercising and trouble sleeping due to fluid buildup in the lungs.
Which treatments are available for individuals diagnosed with heart failure and a preserved ejection fraction?
Treatments often include lifestyle changes, such as a low-sodium diet and regular exercise. Medications like beta-blockers, diuretics, and ACE inhibitors are also commonly used. In some cases, managing underlying conditions like hypertension is crucial.
How does the prognosis of heart failure alter when the ejection fraction is normal?
The prognosis can be quite variable. While the heart’s pumping ability remains normal, the filling problems can lead to ongoing symptoms and complications. Early diagnosis and proper management can help improve your quality of life.
What are the distinctions between heart failure with preserved and reduced ejection fraction?
Heart failure with a preserved ejection fraction involves normal pumping but difficulty in filling the heart with blood during relaxation. In contrast, heart failure with a reduced ejection fraction means the heart’s ability to pump blood is decreased, leading to more pronounced symptoms.
Is it possible to receive a normal echocardiogram result yet still suffer from heart failure?
Yes, it is possible. A normal ejection fraction on an echocardiogram does not rule out heart failure. The condition can be due to diastolic dysfunction, where the heart has issues filling with blood properly.
What steps can be taken to enhance one’s ejection fraction?
To enhance ejection fraction, you can adopt a heart-healthy lifestyle. This includes regular exercise, a balanced diet, and avoiding smoking. Managing stress and controlling risk factors like high blood pressure and diabetes is also vital. Medications prescribed by your doctor can further assist in improving your heart function.

